BETA THALASSEMIA DISEASE

About Sickle Cell Beta Thalassemia Disease in patients with sickle cell Beta Thalassemia Disease, there is a decrease in hemoglobin production which causes smaller red blood cells. 

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When Beta Thalassemia genes are in combination with the sickle gene, it is known as Sickle Cell Beta Thalassemia Disease. 

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There are two kinds of Sickle Cell Beta Thalassemia Disease (SBTHAL):

• Sβ+THAL                                                                                                      

• Sβ°THAL.

 

Individuals with Sβ+THAL have:

• Spleens that function

• Fewer infections

• Fewer pain episodes, and 

• Less organ damage due to Hemoglobin "A" (Normal) not being completely suppressed. 

 

Individuals with Sβ°THAL have:

•Very severe disease — The same as Sickle Cell Anemia.

• Spleens that stop working later in childhood

• Enlargement of the spleen is common in adulthood.

•Pain episodes

• Organ damage

• Prognosis may be similar to, or even worse, for bone and eye problems with compared to sickle cell anemia.